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Concomitantly, mythological narratives and religious beliefs were elaborated that enabled individual integration (McNamara, 2009) and collective accommodation (McKay, 2018; Sterelny, 2018) of the profound, and often unsettling, visionary experiences encountered in ASC. Inventory records for dunbar incorporated revealed the following article. Comparative ethnographic evidence reveals that one of the main shamanistic uses of psychedelics is for divination, i. e., for procuring otherwise unattainable information (Dobkin de Ríos, 1984; Schultes et al., 2001; Rätsch, 2005). In the context of the official religious system, psychedelic mushroom consumption characterized notions of hospitality and ostentatiousness amongst the Mexica elite, and involved intricate ritual performances that included call and response, chanting, and dancing, as described in Hernando de Alvarado Tezozómoc's Crónica Mexicana (written circa 1598) (Frost, 2017). Through a Baldwin effect [a non-Lamarckian way for environmentally induced somatic modifications, resulting from either learning or physiological adaptation, to become heritable changes (Jablonka and Lamb, 1998; Weber and Depew, 2003)], selection for genetic variants that make the acquisition of creativity and sociality faster, more reliable, and less dependent on environmental signals (such as the ritual consumption of psychedelics) would have eventually occurred.

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1007/s00213-015-4026-7. Gabay, A. S., Carhart-Harris, R. L., Mazibuko, N., Kempton, M. J., Morrison, P. D., Nutt, D. Psilocybin and MDMA reduce costly punishment in the Ultimatum Game. Importantly, as meat became a more pervasive item in later hominins' diet, it is likely that tryptophan deficits were less common since it is present in high quantities in most protein-based foods (Friedman, 2018). Girn, M., Mills, C., Roseman, L., Carhart-Harris, R. L., and Christoff, K. Updating the dynamic framework of thought: Creativity and psychedelics. The use of medicinal plants by animals, " in Phytochemical Potentials of Tropical Plants, eds K. Inventory records for Dunbar Incorporated revealed - Gauthmath. Downum, J. T. Romeo, and H. Stafford (New York, NY: Plenum), 89–105.

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Neuroimage 213:116726. De Araujo, D. B., Ribeiro, S., Cecchi, G. A., Carvalho, F. M., Sanchez, T. A., Pinto, J. P., et al. Acta Psychiatrica Scand. Music as a coevolved system for social bonding. A model of psychedelics instrumentalization by early humans, and of the evolutionary consequences of its intergenerational recurrence. Accounting Practice Set II - Biology Forums Resource Library. A., and Kallio-Tamminen, T. Selfhood triumvirate: from phenomenology to brain activity and back again. Van Ginneken, V., van Meerveld, A., Wijgerde, T., Verheij, E., de Vries, E., and van der Greef, J. Hunter-prey correlation between migration routes of African buffaloes and early hominids: evidence for the "Out of Africa" hypothesis. 1038/s41598-018-26656-2. Hence, psychedelic brain states exhibit higher signal complexity (entropy) and higher cognitive flexibility, but lower cause-effect information (Gallimore, 2015). Doctoral Dissertation. Tomasello, M., Melis, A. P., Tennie, C., Wyman, E., and Herrmann, E. Two key steps in the evolution of human cooperation: the interdependence hypothesis. As argued by Ferreira Júnior et al. Current Topics in Behavioral Neurosciences, Vol. While observational evidence shows non-human mammals using plants for their psychoactivity (Siegel, 2005; Forbey et al., 2009) most animals are not particularly fond of mind-altering materials.

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In this context, psychedelics' effects in enhancing sociality, imagination, eloquence, and suggestibility may have increased adaptability and fitness. Early hominins may have lacked these traits (Silk, 2007), but specific selection pressures led to their acquisition in the Homo lineage (Schwartz and Tattersall, 2015). Psychedelics can facilitate adaptive stress coping via upregulation of 5-HT2A receptor functioning (Carhart-Harris and Nutt, 2017), bringing about a "pivotal mental state" characterized by an enhanced rate of associative learning and the potential for the mediation of stress through psychological or cognitive transformations (Brouwer and Carhart-Harris, 2021). This alteration of distributed neural processes manifests as increased synaptic plasticity and entropy, as well as reduced integrity of discrete brain networks (e. g., functional disintegration of the default-mode network [DMN]) and reduced segregation between networks (e. g., increased functional connectivity between the DMN and dorsal attention network) (De Gregorio et al., 2018; Preller et al., 2019, 2020; Madsen et al., 2021). The human niche encompasses face-to-face interactions within social groups, interactions among social groups, and complex social dynamics at both group and larger community levels (Fuentes, 2015). 1007/978-94-007-7067-6_13. He also argued the presence of psychedelics in the early human diet drove the rapid reorganization of the brain's information-processing capacities by catalyzing the emergence of self-reflective consciousness and language. From a homeostatic perspective, increased fitness can potentially result from consumption of psychoactive plants containing compounds that chemically resemble endogenous signaling molecules, especially when internal signaling functions are compromised [e. g., due to deficiencies in dietary precursors in marginal environments (Sullivan and Hagen, 2015)]. For millions of years, this image-based cognitive modality provided hominins with a meta-cognitive system for representation of complex relations, problem-solving, and strategic planning (Lohmar, 2010) despite it being less analytically advanced than the (logical, rule-based, and reflective) secondary process thinking (Carhart-Harris et al., 2014). Evidence of humans' relationships with psychedelics during more recent times (the Holocene) is found in the archeological and paleoethnobotanical record (Guerra-Doce, 2015; Fitzpatrick, 2018; Miller et al., 2019; Samorini, 2019; Robinson et al., 2020). Mason, N. C., Reckweg, J. T., Müller, F., Tse, D. Financial Accounting Midterm Chapter #6 Flashcards. Y., Da Rios, B., et al. Our ancestors might have been particularly drawn to the rapidly ensuing boost in cognitive flexibility, imagination, and optimism, as well as to the visual intensifications and complex imagery linked to intuitive realizations that psychedelics can facilitate (see Table 3 for a summary of behavioral and neuroimaging evidence of potentially fitness-enhancing effects of psychedelics on cognition). The following sections integrate current understanding of the socio-cognitive niche with recent psychedelic research (mainly controlled experimental studies in humans, both in clinical populations and healthy volunteers) to illustrate how psychedelics could have been adaptively employed by our ancestors. Reviewed by:Kyle Summers, East Carolina University, United States.

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's (2011) review of literature on psilocybin risks found that in spite of moderate acute toxicity, psilocybin has low chronic toxicity and negligible public health risk. This notion is suggested by a qualitative reading of the anthropological record, but has yet to be confirmed by more systematic studies. Carhart-Harris, R. L., Muthukumaraswamy, S., Roseman, L., Kaelen, M., Droog, W., Murphy, K., et al. Importantly, archaic humans manifested derived traits such as advanced mindreading capacities, a propensity for shared rhythmical movement and sound, and early precursors of storytelling through mimesis (Sterelny, 2018; Dunbar, 2020). We show that, afterward, psychedelics could have increased adaptability and fitness in the context of this obligatorily cooperative, social-learning-dependent lifestyle because they could be harnessed as "instruments" to enhance performance of non-drug-related behaviors, particularly: to manage psychological distress and treat health problems; to improve social interaction and interpersonal relations; to facilitate collective ritual and religious activities; and to enhance group decision-making. The revolutionary health science of psychoendoneuroimmunology: a new paradigm for understanding health and treating illness. 5-Hydroxytryptamine moderates anxiety and stress, promotes patience and coping, and under conditions of increased environmental volatility, opens a window of plasticity for greater adaptation (Branchi, 2011; Miyazaki et al., 2012; Carhart-Harris and Nutt, 2017). Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Hominin entry into the socio-cognitive niche cannot be explained in terms of a single causal factor, a critical adaptive breakthrough (e. g., bipedality, tool-use, cooking, or even psychedelic use), but instead through positive feedback loops among various aspects of hominin life, an adaptive complex involving novel or greatly exaggerated features of our lineage (Sterelny, 2012). Furthermore, psilocybin shifts emotional biases away from negative toward positive stimuli (Kraehenmann et al., 2016), and a single high-dose experience can engender measurable and long-lasting changes in socially oriented aspects of personality, such as increases in the dimensions of Openness and Extraversion (MacLean et al., 2011; Bouso et al., 2018; Erritzoe et al., 2018). Inventory records for dunbar incorporated revealed the following steps. B) Psychedelic use can amplify symbolic behavior and a predisposition for collective rituals and synchronicity (e. g., by stimulating deployment of rhythmic, hermeneutical, and rhetorical activity to endure, make sense of, and communicate ecstatic and visionary experiences; Doyle, 2011) that could have transformed the social environment, and thus local selection pressures, through cultural niche construction. We argue this is the case because if early enhancements in the tendency to develop social links and cooperate in groups, in creativity, in non-verbal and linguistic expression, or suggestibility were actually produced by psychedelics (as suggested in the section on Psychedelic instrumentalization in the human socio-cognitive niche) they would have transformed the social environment, and thus the selection pressures, for ancient hominins. Hominin encounters with macroscopic fungi growing on the soil surface must constitute a very ancient and continual phenomenon that demanded behavioral adaptations.

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30March 9 Sold 22 units @ 8. Carhart-Harris, R. L., Kaelen, M., Whalley, M. G., Bolstridge, M., Feilding, A., and Nutt, D. (2015). Hallucinations under psychedelics and in the schizophrenia spectrum: an interdisciplinary and multiscale comparison. "Neurobiology of the effects of psilocybin in relation to its potential therapeutic targets, " in Neuropathology of Drug Addictions and Substance Misuse, Vol. 2 School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, United States. Once archaic humans developed religious and spiritual concerns (see following section on Facilitation of collective ritual and religious activities), psilocybin would have become even more useful given its intrinsic ability to produce mystical-type experiences involving the dissolution of self-boundaries and a sense of unity with others (Griffiths et al., 2006, 2011). Carhart-Harris, R. L., Giribaldi, B., Watts, R., Baker-Jones, M., Murphy-Beiner, A., Murphy, R., et al. Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature. Author Contributions. Data Availability Statement. Enjoy live Q&A or pic answer. Uthaug, M. V., Mason, N. L., Toennes, S. W., Reckweg, J. T., de Sousa Fernandes, Perna, E. Inventory records for dunbar incorporated revealed the following information. B., et al. Consequently, psychedelic instrumentalization can be modeled as an enabling factor in the hominization process, as a socially learned and culturally evolved trait (initially an individually learned self-medicative behavior) that assisted in the construction of the socio-cognitive niche. Gauthmath helper for Chrome.

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Psychiatry 39, 1055–1057. As a consequence, memories (and eventually cultural traditions) were formed regarding the identification of these species and the resulting effects of their ingestion. Humans, like all primates, are intensely social. Functioning in this socio-cognitive niche thus required not just intelligence and technological know-how, but more importantly the capacity for cooperation among non-kin and social learning, eventually mediated by language (Barrett et al., 2007; Whiten and Erdal, 2012). Psilocybin ingestion could have provided homeostatic utility to our ancestors as a "treatment" for 5-HT depletion – a recurrent adaptive problem throughout advancement into a socio-cognitive niche. Check the full answer on App Gauthmath. Received: 23 June 2021; Accepted: 06 September 2021; Published: 29 September 2021. Tishkoff, S. A., Reed, F. A., Ranciaro, A., Voight, B. F., Babbitt, C. C., Silverman, J. Convergent adaptation of human lactase persistence in Africa and Europe. Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine. Entry into the socio-cognitive niche involved increasing cognition, sociality, communication, and social learning. White, T. D., Asfaw, B., Beyene, Y., Haile-Selassie, Y., Lovejoy, C. O., Suwa, G., et al. Neuroimage 220:117049. Crucially, divination is a ritual and a tradition involving an ongoing dialog with more-than-human agents (Curry, 2010; Espírito, 2019).

So, while psychedelic instrumentalization may have been an important ancient feature of human social and cognitive lives, it is now largely absent from most human cultures. Moreover, the use of acting and the employment of illusions (e. g., the use of masks and costumes) intentionally seek to affect the thoughts, feelings, or perceptions of the audience, bringing about emotional arousal and the evocation of faith, hope, and trust that ultimately enhance client expectations (Krippner, 2002). Recommended textbook solutions. Natural landscapes are a diverse combination of plant species that are literally nutrition centers and pharmacies with a wide range of primary (nutrient) and secondary (pharmaceutical) compounds vital to the health of plants and herbivores (Villalba and Provenza, 2007). Cross-culturally, ritual specialists leverage collective, socially bonding mythic narratives and coordinated, mixed modality performances of entrained ritual or dance to provide structuring during ego-dissolution and to evoke culturally expected visions through expressive dimensions of ritual (Dobkin de Ríos, 1984; Winkelman, 2002, 2015, 2021c; Rodríguez and Quirce, 2012). 2021) lends support to this hypothesis, showing that communitas – an intense sense of togetherness and shared humanity – mediates enduring increases in psychological well-being and social connectedness following psychedelic use in ceremonial retreats. Madsen, M. K., Stenbæk, D. S., Arvidsson, A., Armand, S., Marstrand-Joergensen, M. R., Johansen, S. S., et al. "Shamanism and the alteration of consciousness, " in Altering Consciousness Multidisciplinary Perspectives Volume 1: History, Culture and the Humanities, eds E. Cardeña and M. Winkelman (Santa Barbara, CA: Praeger ABC-CLIO), 159–180.
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