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July 21, 2024, 8:32 am

I was sick and tired — and more than a bit bored — of spending so much time with the self-important, amoral and insanely rich Sackler family. Keefe writes well, and Empire of Pain reads like a fast-paced novel. This proved to be a very compelling marketing hook — the drug would end up generating $35 billion in revenue — but it was also a lie. He also explains that a large portion of the depositions, law enforcement files, and internal Purdue records he used to report the story arrived in his mailbox via an anonymous thumb drive (he was in the process of a Freedom of Information Act suit against the FDA at the time). "My parents brainwashed me about being a doctor. " Keefe turns up plenty of answers, including the details of how the Sacklers—the first generation of three brothers, followed by their children and grandchildren—marketed their goods, beginning with "ethical drugs" (as distinct from illegal ones) to treat mental illness, Librium and then Valium, which were effectively the same thing but were advertised as treating different maladies: "If Librium was the cure for 'anxiety, ' Valium should be prescribed for 'psychic tension. ' They may have more money that 99. And one of them wouldn't talk with me and three of them are dead. I'm also always looking for characters. Rachel Maddow, host of MSNBC's "The Rachel Maddow Show" and author of the #1 New York Times bestselling Blowout.

Empire Of Pain Book Club Questions And

Kentucky was the first to depose Richard Sackler in person, and the contents of that deposition have been front and center on subsequent suits. And then, in 2019, when you got ahold of the court filing documents for this Massachusetts Sackler case, you put some of the biggest revelations on Twitter. Thank you to our event sponsor: Now Radden Keefe is back with another investigative turn, Empire of Pain: The Secret History of the Sackler Dynasty.

I think the big question with the Sacklers has always been what did they know and when did they know it? Among other good ideas, the smartest people in that room suggested offering a rebate "each time a patient who had been prescribed OxyContin subsequently overdosed or developed an opioid use disorder. " Loved the 'interview' format. I wanted to get as close as I could. As he explains, in his final attempt to get answers from the Sacklers, he sent a lengthy memo of queries, by request, to a family lawyer. As a reader, there are moments in which we want more from him; it would occasionally be a more satisfying read if he couched the reporting in his personal stories or reactions. Such was the family's generosity that few asked: Where did all this wealth come from? Exhaustively researched and written with grace and gravity, Empire of Pain unpeels a most terrible American scandal. There was this idea of doctors as being an example of wisdom and probity. "A shocking saga… [a]tour-de-force account… [Keefe] brings to life the obsessive personalities and ferocious energy of some members…The Sacklers emerge as a shameless bunch, but Empire of Pain also poses troubling questions about the US healthcare system that permitted them to flourish. " If they got their messaging right, Purdue could exploit the misperception and market OxyContin, their new drug, as safer than morphine, though it was actually about twice as strong. The decisions that birthed and perpetuated the epidemic were not made by employees or a management team, he reveals, but by members of this cultured clan of physicians, long acclaimed for their arts philanthropy... As Keefe ably demonstrates, it was the Sacklers who dreamed up OxyContin as a solution to an anticipated revenue decline, and it was the Sacklers who insisted their powerful narcotic, the sort of drug previously reserved for terminal patients, be marketed aggressively and widely... And just by coincidence, reformulation happened when the original patents were about to run out. Arthur Sackler was born in Brooklyn, in the summer of 1913, at a moment when Brooklyn was burgeoning with wave upon wave of immigrants from the Old World, new faces every day, the unfamiliar music of new tongues on the street corners, new buildings going up left and right to house and employ these new arrivals, and everywhere this giddy, bounding sense of becoming.

Two years later, he was the firm's president and on his way to pioneering many of the techniques we now associate with pharmaceutical sales, such as courting physicians with free meals and creating "native advertising" that looked like independent editorial content. I tend to like to do a lot of interviews for a bunch of reasons, in part because I'm always looking for stories and I really like to corroborate things as best I can, find as many people who were around. They continued to sell the drug using many of the same methods as before, such as distributing literature claiming that it was less prone to cause addiction than other, older pain medications. Currently available through our local booksellers Andersons Books and Voracious Reader. In Keefe's new book, Empire of Pain: The Secret History of the Sackler Dynasty, the journalist tells the story of how the Sacklers came to be so rich, so influential, and, ultimately, so reviled. Some of the Founding Fathers whom Artie Sackler so revered had been supporters of the school he now attended: Alexander Hamilton, Aaron Burr, and John Jay had contributed funds to Erasmus. He writes about an immigrant Jewish couple in Brooklyn who gave birth to three brothers — Arthur, Mortimer and Raymond. Like Elizabeth, I'm not sure I would've gotten through the print version. A disturbing story leaving little doubt that the Sacklers were aware of the impact that their drug was having and how they actively worked to get it into the hands of millions of people across the globe. AB: Well, your last book, Say Nothing, and this book are about two groups that have a kind of baked-in silence. In many respects, they are reminiscent of the appalling Roys in the TV series Succession, galvanised by astonishing profits but fundamentally removed from the world they are busy despoiling. But they aren't a rare case.

Empire Of Pain Discussion Questions

Instead, he writes, company officials saw the penalties as a "speeding ticket. " Patrick Radden Keefe is a staff writer at The New Yorker and the author of Empire of Pain. Erasmus issued "program cards" and other pieces of humdrum curricular paperwork to its eight thousand students. On the contrary, he had bestowed upon them something more valuable than money. In his hands, their story becomes a great American morality tale about unvarnished greed dressed in ostentatious philanthropy. " Should they all not be charged with genocide and their past crimes against humanity? For me, part of what makes this so tragic is that in some ways, this is a story about idealism and a kind of idealistic bet that turned out to be a bad bet. Each day, Arthur and his fellow students were inculcated with the idea that they would eventually take their place in a long line of great Americans, a continuous line that stretched back to the country's founding. Looked at another way, they've lost big. And here's another shocker: the FDA agreed. Readers will be outraged and enthralled in equal measure.

Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. When you're twenty years old, it's really fun to spend time with somebody like that. Data can be adduced, for example, to answer the question of whether immigration tends to suppress wages. It's seductive and exciting. He was accumulating new jobs more quickly than he could work them, so he started to hand some of them off to his brother Morty.

ISBN: 9780593238714. Thus, when asked whether she acknowledged that hundreds of thousands of Americans had become addicted to OxyContin, Kathe answered, "I don't know the answer to that. " AB: You spoke to something like two hundred sources, right? So that was one big thing, being able to substantiate lots of lots and lots of very high-level conversations about problems, starting really in '97. But the story lives on in Keefe's book — juxtaposed, as it should be, with that of the Sacklers. Arthur arranged for his brothers to sell advertising for The Dutchman, the student magazine at Erasmus. For me, it was almost like a decoder ring, realizing that it's all about the patent.

Empire Of Pain Book Review

When the Great Depression hit in 1929, Isaac Sackler's misfortune intensified. Such a relevant topic for a book and for a discussion–raises all sort of questions about institutional corruption within our ultra capitalistic society. I probably jumped to heroin within that same year. They are one of the richest families in the world, but the source of the family fortune was vague—until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. 19 The Pablo Escobar of the New Millennium 239. The cars, houses, and cell phone bills of the third generation of Sacklers were paid for with OxyContin money, but they've historically dodged questions regarding from where the wealth derived. Executives in the company, and even the Sacklers themselves, have told people under oath that they only learned there was any kind of problem with people misusing OxyContin through press reports in the spring of 2000. For me, Say Nothing was very much a story of moral ambiguity. Nor was he content with the one job.

The payouts of up to $14, 000 per sufferer wouldn't go directly to those afflicted, however, but to the pharmacies and insurance companies who paid for the drug, to encourage them not to let up on prescriptions, "even in the face of such potentially lethal side effects. Keefe quotes Richard Sackler, who at the time was the company's president, telling colleagues that "these are criminals, why should they be entitled to our sympathies? " It's a very hard issue. Review Posted Online: Aug. 29, 2019. They dispatched doctors around the country to tout the benefits of OxyContin, how it was, as its motto said, "The one to start with and the one to stay with. They said generic makers can't make this drug that Purdue has already been selling for 15 years at that point.

Pub Date: Feb. 21, 2023. He intended to charge Friedman, Goldenheim, and Udell with the crimes of money laundering, wire fraud, and mail fraud. As the Covid-19 pandemic begins to fizzle in the U. S., a very different kind of epidemic still rages. Even after the bankruptcy and shaming, Keefe writes, the Sacklers largely held onto their money, because they had extracted most of their fortune from the company and placed it in private holdings.

With that statement, the author updates an argument as old as Marx and Proudhon. In doing so, however, they were enabled by public officials and by the American business ethos. Keefe shows how three generations of the Sacklers — beginning with founding brothers Arthur, Raymond, and Mortimer — acquired a $13 billion fortune and fueled a public health crisis by using sales, marketing, and other tactics that ranged from trailblazing to hardball to outright criminal. What do you think it reveals about the pharmaceutical industry in America?

Immigration, trade, inequality, and taxation problems present themselves daily, and they seem to be intractable. Has that changed after writing this book?

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